Поздняя нейротоксичность противоопухолевого лечения у детей: часть 2 (С.А. Кулева, М.Б. Белогурова, Б.А. Колыгин)

S.A. Kulyova, M.B. Belogurova, B.A. Kolygin

Аннотация


В настоящее время появилось множество исследований об отсроченных нейрокогнитивных дефицитах у детей, лечившихся от злокачественных опухолей. Степени дисфункций являются следствием комплекса факторов, зависящих от возраста ребенка, нейроанатомического повреждения, обусловленного самой опухолью, хирургическим лечением, радио- и химиотерапией и др. Многие вылечившиеся пациенты имеют повышенные риски не только в обучении, но и психологическом и социальном развитии.
Ключевые слова: дети, рак, лечение, отдаленные нейрокогнитивные дисфункции.

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Литература


Weiner S.L., Simone J.V., Hewitt M. Childhood cancersurv ivorship: improving care and quality of life. Washington, DC. Nat Ac Sci. 2003; 32.

Oeffinger K.C., Hudson M.M. Long-term complication following childhood and adolescent cancer: foundation for providing risk-based health care for survivors. CA: A Cancer J Clin. 2004; 54: 208–36.

Ries L.A., Eisner M.P., Kosary C.L. et al. (eds.). SEER Cancer Statistics Review, 1975–2000. National Cancer Institute, Bethesda, M.D. 2003.

Meadows A.T., Krejmas N.L., Belasco J.B. The medical cost of cure: sequalae in survivors of childhood cancer. In: Status of the curability of childhood cancer. Van Eysp., Sullivan M. (eds). New York: Raven Press. 1980. Р. 263–276.

Moleski M. Neuropsychological, neuroanatomical, and neurophysiological consequences of CNS chemotherapy for acute lymphoblastic leukemia. Arch Clin Neuropsychol. 2000; 15: 603–630.

Rubenstein C.L., Varni J.W., Katz E.R. Cognitive functioning in long-term survivors of childhood leukemia: a prospective analysis. Dev Behav Pediatr. 1990; 11: 301–5.

Mulhern R.K., Fairclough D., Ochs J. A prospective comparison of neuropsychologic performance of children surviving leukemia who received 18 Gy, 24 Gy, or no cranial irradiation. J Clin Oncol. 1991; 9: 1348–56.

Espy K.A., Moore I.M., Kaufmann P.M., Kramer J.H., Matthay K., Hutter J.J. Chemotherapeutic CNS prophylaxis and neuropsychologic change in children with acute lymphoblastic leukemia: a prospective study. J Pediatr Psychol. 2001; 26: 1–9.

Waber D.P., Carpentrieri S.C., Klar N., Silverman L.B., Schwenn M., Hurwitz C.A., Mullenix P.J., Tarbell N.J., Sallan S.E. Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone. J Pediatr Hematol Oncol. 2000; 22: 206–13.

Posner M.I., Peterson S.E. The attention system of the human brain. Annu Rev Neurosci. 1990; 13: 25–42.

Lockwood K.A., Bell T.S., Colegrove R.W. Long-term effects of cranial radiation therapy on attention functioning in survivors of childhood leukemia. J Pediatr Psychol. 1999; 24: 55–66.

Rodgers J., Horrocks J., Britton P.G., Kernahan J. Attention ability among survivors of leukaemia. Arch Dis Child. 1999; 80: 318–23.

Schatz J., Kramer J.H., Ablin A., Matthay K.K. Processing speed, working memory, and IQ: a developmental model of cognitive deficits following cranial radiation therapy. Neuropsychology. 2000; 14: 18–200.

Hudson M.M., Mertens A.C., Yasui Y., Hobbie W., Chen H., Gurney J.G., Yeazel M., Recklitis C.J., Marina N., Robison L.R., Oeffinger K.C. Health status of adult long-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. JAMA. 2003; 290: 1583–92.

Recklitis C.J., Diller L.R., Li X., Najita J., Robison L.L., Zeltzer L. Suicide ideation in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2010; 28 (4): 655–61.

Waber D.P., Urion D.K., Tarbell N.J., Niemeyer C., Gelber R., Sallan S.E. Late effects of central nervous system treatment of acute lymphoblastic leukemia in childhood are sex-dependent. Dev Med Child Neurol. 1990; 32: 238–48.

Kaleita T.A., Shields W.D., Tesler A., Feig S. Normal neurodevelopment in four young children treated for acute leukemia or aplastic anemia. Pediatrics. 1989; 83: 753–7.

Pot-Mees C.C. The psychological aspects of bone marrow transplantation in children. Delft: Eburon. 1989.

Smedler A.C., Nilsson C., Bolm P. Total body irradiation: a neuropsycholodical risk factor in pediatric bone marrow transplant recipients. Acta Pediatr. 1995; 84: 325–30.

McGuire T., Sanders J.E., Hill J.D. Neuropsychological function in children given total body irradiation for marrow transplantation. Exp Hematol. 1991; 19: 578.

Kramer J.H., Crittenden M.R., DeSantes K., Cowan M.J. Cognitive and adaptive behavior 1 and 3 years following bone marrow transplantation. Bone Marrow Transplant. 1997; 19: 607–13.

Phipps S., Brenner M., Heslop H., Krance R., Jayawardene D., Mulhern R. Psychological effects of bone marrow transplant on children: preliminary report of a longitudinal study. Bone Marrow Transplant. 1995; 16: 829–35.

Phipps S., Dunavant M., Srivasatava D.K., Bowman L., Mulhern R.K. Cognitive and academic functioning in survivors of pediatric bone marrow transplantation. J Clon Oncol. 2000; 18: 1004–11.

Simms S., Kazak A.E., Gannon T., Goldwein J., Bunin N. Neuropsychological outcome of children undergoing bone marrow transplantation. Bone Marrow Transplant. 1998; 22: 181–4.

Arvidson J., Kihlgren M., Hall C., Lonnerholm G. Neuropsychological functioning after treatment for hematologic malignancies in childhood, including autologous bone marrow transplantation. Pediatr Hematol Oncol. 1999; 16: 9–21.

Daniel Llach M., Perez Campdepadros M., Baza Ceballos N., Igual Brull L., Badell Serra I., Puig Reichach T., Cubells Rieró J. Secuelas neuropsicologicas a medio y largo plazo del trasplante de medulla osea en pacientes con enfermedades heamtologicas. Anales Pediatria. 2001; 54: 463–7.


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